Quinapril HCl (CI-906)

This product is for research use only, not for human use. We do not sell to patients.

Quinapril HCl (CI-906)
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
50mg$553-6 Days
100mg$803-6 Days
250mg$1203-6 Days
500mg$1803-6 Days
1g$2803-6 Days
10g$13803-6 Days

Cat #: V1785 CAS #: 82586-55-8 Purity ≥ 98%

Description: Quinapril HCl (formerly CI-906, PD-109452-2; Acequin; Korec; Accupril; Accuprin; Accupril), the hydrochloride salt form of quinapril which is the prodrug of quinaprilat, is an angiotensin-converting enzyme/ACE inhibitor with anti-hypertensive effects. It is an approved antihypertensive drug that inhibits ACE with a Ki of 20 μM. Quinapril is a prodrug that has to to be converted in vivo to its active metabolite, quinaprilat.

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Molecular Weight (MW)474.98
Molecular FormulaC25H30N2O5.HCl
CAS No.82586-55-8
Storage-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 95 mg/mL (200.0 mM)
Water: 95 mg/mL (200.0 mM)
Ethanol: 95 mg/mL (200.0 mM)
SynonymsCI 906; PD-109452-2; CI-906; PD 109452-2; CI-906; PD-109,452-2; Accupril; Accuprin; Acequin; Korec; Accupril; quinapril
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.1054 mL10.5268 mL21.0535 mL42.1070 mL
5mM0.4211 mL2.1054 mL4.2107 mL8.4214 mL
10mM0.2105 mL1.0527 mL2.1054 mL4.2107 mL
20mM0.1053 mL0.5263 mL1.0527 mL2.1054 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.