Candesartan Cilexetil (CV 11974)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 50g | $545 | Check With Us |
| 100g | $817 | Check With Us |
| 200g | $1225 | Check With Us |
: Cat #: V1784 CAS #: 145040-37-5 Purity ≥ 98%
Description: Candesartan Cilexetil (formerly TCV-116; CV11974; CV-11974; Atacand), an ester prodrug of Candesartan, is an antihypertensive drug acting as an AT II/angiotensin II receptor antagonist with anti-hypertensive effects.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 610.66 |
|---|---|
| Molecular Formula | C33H34N6O6 |
| CAS No. | 145040-37-5 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 122 mg/mL (199.8 mM)r |
| Water: <1 mg/mLr | |
| Ethanol: 4 mg/mL (6.6 mM) | |
| Synonyms | CV-11974; TCV-116; CV 11974; TCV 116; CV11974; TCV116 |
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 1.6376 mL | 8.1879 mL | 16.3757 mL | 32.7514 mL |
| 5mM | 0.3275 mL | 1.6376 mL | 3.2751 mL | 6.5503 mL |
| 10mM | 0.1638 mL | 0.8188 mL | 1.6376 mL | 3.2751 mL |
| 20mM | 0.0819 mL | 0.4094 mL | 0.8188 mL | 1.6376 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.