Captopril (SQ-14534; SA333)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 5g | $250 | Check With Us |
| 10g | $400 | Check With Us |
| 20g | $600 | Check With Us |
: Cat #: V1792 CAS #: 62571-86-2 Purity ≥ 98%
Description: Captopril (SQ 14225; SA333) is a potent angiotensin-converting enzyme (ACE) inhibitor with IC50 of 6 nM.
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| Molecular Weight (MW) | 217.29 |
|---|---|
| Molecular Formula | C9H15NO3S |
| CAS No. | 62571-86-2 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 43 mg/mL (197.9 mM)r |
| Water: 2 mg/mL (9.2 mM)r | |
| Ethanol: 43 mg/mL (197.9 mM) | |
| Synonyms | Capoten, SQ14225, SQ 14225, SQ-14225, SQ14,225, SQ 14,225, SQ-14,225 |
| Protocol | In Vitro | Captopril (SQ 14225) has been shown to have similar morbidity and mortality benefits as diuretics and β-blockers in patients with hypertension. Captopril has been shown to delay the progression of diabetic nephropathy, while Enalapril and Lisinopril prevent the development of nephropathy in patients with normal albuminuria diabetes |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 4.6021 mL | 23.0107 mL | 46.0214 mL | 92.0429 mL |
| 5mM | 0.9204 mL | 4.6021 mL | 9.2043 mL | 18.4086 mL |
| 10mM | 0.4602 mL | 2.3011 mL | 4.6021 mL | 9.2043 mL |
| 20mM | 0.2301 mL | 1.1505 mL | 2.3011 mL | 4.6021 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.