ACP-105
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 500mg | $1950 | Check With Us |
| 1g | $3250 | Check With Us |
| 5g | $8775 | Check With Us |
: Cat #: V10225 CAS #: 899821-23-9 Purity ≥ 99%
Description: ACP-105 (ACP105; ACP 105) is a novel, nonsteroidal and orally bioactive SARM (selective androgen receptor modulator) that has been investigated for the treatment of age-related cognitive decline.
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| Molecular Weight (MW) | 290.79 |
|---|---|
| Molecular Formula | C16H19ClN2O |
| CAS No. | 899821-23-9 |
| SMILES Code | N#CC1=CC=C(N2[C@@]3([H])CC(C)(O)C[C@@]2([H])CC3)C(C)=C1Cl |
| Synonyms | ACP 105; ACP-105; ACP105 |
| Protocol | In Vitro | ACP-105 is an orally available, selective amd potent androgen receptor modulator (SARM), with pEC50s of 9.0 and 9.3 for AR wild type and T877A mutant, respectively. The half-lives of ACP-105 (compound 1) in human hepatocytes is measured and found to be 5.0 h |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 3.4389 mL | 17.1945 mL | 34.3891 mL | 68.7782 mL |
| 5mM | 0.6878 mL | 3.4389 mL | 6.8778 mL | 13.7556 mL |
| 10mM | 0.3439 mL | 1.7195 mL | 3.4389 mL | 6.8778 mL |
| 20mM | 0.1719 mL | 0.8597 mL | 1.7195 mL | 3.4389 mL |
The molarity calculator equation
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The dilution calculator equation
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This equation is commonly abbreviated as: C1 V1 = C2 V2
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Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.