Phillyrin
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 500mg | $350 | Check With Us |
| 1g | $550 | Check With Us |
| 5g | $1395 | Check With Us |
: Cat #: V34332 CAS #: 487-41-2 Purity ≥ 99%
Description: Phillyrin is naturally occurring lignan compound with anti-inflammatory activity.
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| Molecular Weight (MW) | 534.55 |
|---|---|
| Molecular Formula | C27H34O11 |
| CAS No. | 487-41-2 |
| SMILES Code | O[C@H]([C@H]([C@H]([C@@H](CO)O1)O)O)[C@H]1OC2=CC=C(C3OC[C@@]4([H])[C@]3([H])COC4C5=CC=C(OC)C(OC)=C5)C=C2OC |
| Synonyms | Phillyrin |
| Protocol | In Vitro | Phillyrin (1–5 μM; pretreatment 1 hour; 24 hours) inhibits high glucose-induced FAS mRNA expression by suppressing SREBP-1c activation in human HepG2 hepatocytes. Phillyrin (1–5 μM; pretreatment 1 hour; 24 hours) inhibits high glucose-induced FAS protein significantly in HepG2 cells. |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 1.8707 mL | 9.3537 mL | 18.7073 mL | 37.4146 mL |
| 5mM | 0.3741 mL | 1.8707 mL | 3.7415 mL | 7.4829 mL |
| 10mM | 0.1871 mL | 0.9354 mL | 1.8707 mL | 3.7415 mL |
| 20mM | 0.0935 mL | 0.4677 mL | 0.9354 mL | 1.8707 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.