Dexamethasone palmitate (DXP)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 500mg | $750 | Check With Us |
| 1g | $1250 | Check With Us |
| 5g | $3375 | Check With Us |
: Cat #: V19657 CAS #: 14899-36-6 Purity ≥ 98%
Description: Dexamethasone palmitate, the palmitate salt and a prodrug of Dexamethasone with anti-inflammatory and immunosuppressant activities, is a liposteroid for treatment of hemophagocytic lymphohistiocytosis.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 645.87 |
|---|---|
| Molecular Formula | C38H58FO7 |
| CAS No. | 14899-36-6 |
| Synonyms | DXP; Limethason; Dexamethasone 21-palmitate |
| Protocol | In Vivo | Dexamethasone palmitate (1280 μg; IVT injection once) shows different distribution in ocular tissue at different times |
|---|---|---|
| Animal model | New Zealand White rabbits | |
| Dosages | 1280 μg | |
| Administration | IVT injection; 1280 μg once |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 1.5483 mL | 7.7415 mL | 15.4830 mL | 30.9660 mL |
| 5mM | 0.3097 mL | 1.5483 mL | 3.0966 mL | 6.1932 mL |
| 10mM | 0.1548 mL | 0.7741 mL | 1.5483 mL | 3.0966 mL |
| 20mM | 0.0774 mL | 0.3871 mL | 0.7741 mL | 1.5483 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.