Beclomethasone dipropionate (Beclomethasone)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 2g | $320 | Check With Us |
| 5g | $480 | Check With Us |
| 10g | $720 | Check With Us |
: Cat #: V1716 CAS #: 5534-09-8 Purity ≥ 98%
Description: Beclomethasone dipropionate (also called BDP; Clenil; Qvar; Beconase; alanase; Vancenase) is a topical anti-inflammatory corticosteroid approved for use in treatment of asthma and rhinitis.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 521.04 |
|---|---|
| Molecular Formula | C28H37ClO7 |
| CAS No. | 5534-09-8 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 104 mg/mL (199.6 mM)r |
| Water: <1 mg/mLr | |
| Ethanol: 18 mg/mL (34.5 mM) | |
| Synonyms | Beclomethasone dipropionate; Clenil; Qvar; Beconase; alanase; Vancenase; Beclometasone dipropionate |
| Protocol | In Vivo | Beclometasone dipropionate (150 µg/kg; nebulization; male BALB/c mice) relieves asthma and decreases total cell number and relative eosinophil number |
|---|---|---|
| Animal model | Ten-week-old male Balb/c mice | |
| Dosages | 5 mg/kg (100 μg/ml for 60 min). | |
| Administration | Orally at 24 h and 1 h before the LPS aerosol. |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 1.9192 mL | 9.5962 mL | 19.1924 mL | 38.3848 mL |
| 5mM | 0.3838 mL | 1.9192 mL | 3.8385 mL | 7.6770 mL |
| 10mM | 0.1919 mL | 0.9596 mL | 1.9192 mL | 3.8385 mL |
| 20mM | 0.0960 mL | 0.4798 mL | 0.9596 mL | 1.9192 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.