AC-262536
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 500mg | $550 | In Stock |
| 1g | $900 | In Stock |
| 5g | $2280 | In Stock |
: Cat #: V8411 CAS #: 870888-46-3 Purity ≥ 98%
Description: AC-262536 (AC262536) is a novel selective androgen receptor modulator (SARM) with beneficial anabolic effects.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 278.35 |
|---|---|
| Molecular Formula | C18H18N2O |
| CAS No. | 870888-46-3 |
| SMILES Code | N#CC1=C2C=CC=CC2=C(N3[C@@H]4CC(O)C[C@H]3CC4)C=C1 |
| Synonyms | AC-262536; AC 262536; AC262536 |
| Protocol | In Vitro | AC-262536 dose-dependently inhibits dihydroxytestosterone (DHT)-induced proliferation of LNCaP. The effects are significant with 100 nM AC-262536 (%inhibition 47.2±12.2), and reaches a plateau with 1 μM treatment (%inhibition 50.7±7.6). Thus, AC-262536 can act as a functional antagonist in prostate cells. |
|---|---|---|
| In Vivo | AC-262536 (3, 10, 30 mg/kg) reverses the luteinizing hormone (LH) spike in castrated rats. |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 3.5926 mL | 17.9630 mL | 35.9260 mL | 71.8520 mL |
| 5mM | 0.7185 mL | 3.5926 mL | 7.1852 mL | 14.3704 mL |
| 10mM | 0.3593 mL | 1.7963 mL | 3.5926 mL | 7.1852 mL |
| 20mM | 0.1796 mL | 0.8981 mL | 1.7963 mL | 3.5926 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.