(+)-Tetrabenazine

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
250mg	$400	Check With Us
500mg	$700	Check With Us
1g	$1050	Check With Us

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Cat #: V34109 CAS #: 1026016-83-0 Purity ≥ 99%

Description: (+)-Tetrabenazine ((+)-TBZ; (3R,11bR)-TBZ; (3R,11bR)-Tetrabenazine) is a potent and reversible inhibitor of vesicular monoamine transporter 2 (VMAT-2) which inhibits transport by VMAT2 with 10-fold greater potency than transport by VMAT1.

References: Podurgiel SJ et al. The MAO-B inhibitor deprenyl reduces the oral tremor and the dopamine depletion induced by the VMAT-2 inhibitor tetrabenazine. Behav Brain Res. 2016 Feb 1;298(Pt B):188-91.

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Molecular Weight (MW)	317.42
Molecular Formula	C₁₉H₂₇NO₃
CAS No.	1026016-83-0
Synonyms	(+)-TBZ; (3R,11bR)-TBZ; (3R,11bR)-Tetrabenazine

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	3.1504 mL	15.7520 mL	31.5040 mL	63.0080 mL
5mM	0.6301 mL	3.1504 mL	6.3008 mL	12.6016 mL
10mM	0.3150 mL	1.5752 mL	3.1504 mL	6.3008 mL
20mM	0.1575 mL	0.7876 mL	1.5752 mL	3.1504 mL

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.