Estradiol dipropionate

This product is for research use only, not for human use. We do not sell to patients.

Estradiol dipropionate
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
500mg$400Check With Us
1g$650Check With Us
5g$1645Check With Us

Cat #: V11151 CAS #: 113-38-2 Purity ≥ 98%

Description: Estradiol dipropionate, specifically, 17-Beta-Estradiol-3,17-Dipropionate, is a semisynthetic, steroidal estrogen compound.

References: A G Gunin, et al. Uterine Response to Estradiol Under Action of Chorionic Gonadotropin in Mice. Int J Gynecol Cancer. Jul-Aug 2003;13(4):485-96.

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Molecular Weight (MW)384.51
Molecular FormulaC24H32O4
CAS No.113-38-2
SMILES CodeC[C@@]12[C@@H](OC(CC)=O)CC[C@@]1([H])[C@]3([H])CCC4=C(C=CC(OC(CC)=O)=C4)[C@@]3([H])CC2
SynonymsEstradiol dipropionate; Estroici; Estronex; Follicyclin P
ProtocolIn VitroTreatment of Estradiol dipropionate (2 μg per 100 g; once a week) and Chorionic gonadotropin ((10 IU per 100 g; once a day) for a month, the incidence of atypical endometrial hyperplasia is significantly higher, the level of β-catenin is slightly higher, and the expression of GSK-3β is lower in luminal and glandular epithelia. Treatment of Estradiol dipropionate (2μg per 100 g; single subcutaneous injection) and Chorionic gonadotropin (10 IU per 100 g; sc; twice a day) for 2 days, levels of β-catenin and GSK-3β in luminal and glandular epithelia are lower in Ovariectomized mice.
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.6007 mL13.0036 mL26.0071 mL52.0143 mL
5mM0.5201 mL2.6007 mL5.2014 mL10.4029 mL
10mM0.2601 mL1.3004 mL2.6007 mL5.2014 mL
20mM0.1300 mL0.6502 mL1.3004 mL2.6007 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.