PHTPP
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 250mg | $657 | Check With Us |
| 500mg | $986 | Check With Us |
| 1g | $1479 | Check With Us |
: Cat #: V3204 CAS #: 805239-56-9 Purity ≥ 98%
Description: PHTPP is an antagonist of the ERβ (Estrogen Receptor).
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
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| Molecular Weight (MW) | 423.31 |
|---|---|
| Molecular Formula | C20H11F6N3O |
| CAS No. | 805239-56-9 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: > 50 mg/mLr |
| Water: < 1 mg/mLr | |
| Ethanol: > 80 mg/mL | |
| SMILES Code | OC1=CC=C(C2=C3N=C(C(F)(F)F)C=C(C(F)(F)F)N3N=C2C4=CC=CC=C4)C=C1 |
| Synonyms | PHTPP |
| Protocol | In Vitro | PHTPP is a selective ERβ antagonist. PHTPP reduces FSH-mediated cAMP production by 80% (p<0.01) while it has no effect on basal cAMP. |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.3623 mL | 11.8117 mL | 23.6233 mL | 47.2467 mL |
| 5mM | 0.4725 mL | 2.3623 mL | 4.7247 mL | 9.4493 mL |
| 10mM | 0.2362 mL | 1.1812 mL | 2.3623 mL | 4.7247 mL |
| 20mM | 0.1181 mL | 0.5906 mL | 1.1812 mL | 2.3623 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.