E3 ligase Ligand 5
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 500mg | $2080 | To Be Confirmed |
| 1g | $3050 | To Be Confirmed |
| 5g | $7720 | To Be Confirmed |
: Cat #: V4061 CAS #: 1264754-13-3 Purity ≥ 98%
Description: E3 ligase Ligand 5 is an E3 ligase Ligand that can be used in the synthesis of PROTACs (proteolysis targeting chimeras) to engage an E3 ubiquitin ligase.
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- Physicochemical and Storage Information
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- Related Biological Data
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| Molecular Weight (MW) | 420.36 |
|---|---|
| Molecular Formula | C₁₉H₁₁F₃N₂O₄S |
| CAS No. | 1264754-13-3 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 10 mMr |
| Water: N/Ar | |
| Ethanol: N/A | |
| SMILES Code | N#CC1=CC=C(OC2=CC=C(/C=C(SC(N3)=O)/C3=O)C=C2OC)C(C(F)(F)F)=C1 |
| Synonyms | E3 ligase Ligand 5; E3 ligase Ligand-5 |
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.3789 mL | 11.8946 mL | 23.7891 mL | 47.5783 mL |
| 5mM | 0.4758 mL | 2.3789 mL | 4.7578 mL | 9.5157 mL |
| 10mM | 0.2379 mL | 1.1895 mL | 2.3789 mL | 4.7578 mL |
| 20mM | 0.1189 mL | 0.5947 mL | 1.1895 mL | 2.3789 mL |
The molarity calculator equation
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The dilution calculator equation
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Volume(start)
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This equation is commonly abbreviated as: C1 V1 = C2 V2
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Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.