Vecuronium Bromide (ORG NC 45)

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
500mg	$550	Check With Us
1g	$850	Check With Us
5g	$2300	Check With Us

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Cat #: V2036 CAS #: 50700-72-6 Purity ≥ 98%

Description: Vecuronium (ORG NC 45) is a non-depolarizing neuromuscular blocking agent widely used as an adjunct to general anesthesia, to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation.

References: K Uryu, et al. Inhibition by neuromuscular blocking drugs of norepinephrine transporter in cultured bovine adrenal medullary cells. Anesth Analg. 2000 Sep;91(3):546-51.

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Physicochemical and Storage Information
Protocol
Related Biological Data
Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	637.73
Molecular Formula	C34H57N2O4.Br
CAS No.	50700-72-6
Storage	-20℃ for 3 years in powder formr
Storage	-80℃ for 2 years in solvent
Solubility In Vitro	DMSO: 100 mg/mL (156.8 mM)r
	Water: 4 mg/mL (6.3 mM)r
	Ethanol: 100 mg/mL (156.8 mM)
Synonyms	ORG NC45; C 45; NC-45; NC45; ORG NC 45; ORG NC45; ORG-NC 45; ORG-NC-45; ORG-NC45; ORGNC 45; ORGNC45; Vecuronium bromide. Brand name Norcuron

Protocol	In Vitro	Vecuronium bromide (0-100 μM, 15 min) inhibits [3H] norepinephrine (NE) uptake to 65% at 100 μM in adrenal medullary cells

These protocols are for reference only. InvivoChem does not independently validate these methods.

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	1.5681 mL	7.8403 mL	15.6806 mL	31.3612 mL
5mM	0.3136 mL	1.5681 mL	3.1361 mL	6.2722 mL
10mM	0.1568 mL	0.7840 mL	1.5681 mL	3.1361 mL
20mM	0.0784 mL	0.3920 mL	0.7840 mL	1.5681 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.