Atracurium Besylate (BW-33A)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 500mg | $250 | Check With Us |
| 1g | $450 | Check With Us |
| 5g | $1215 | Check With Us |
: Cat #: V2007 CAS #: 64228-81-5 Purity ≥ 98%
Description: Atracurium Besylate (also called BW 33A, 51W89) is a neuromuscular blocking agent that acts as a nondepolarizing, skeletal muscle relaxant with ED95 of 0.2 mg/kg.
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| Molecular Weight (MW) | 1243.48 |
|---|---|
| Molecular Formula | C53H72N2O12.2(C6H5O3S) |
| CAS No. | 64228-81-5 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 100 mg/mL (80.4 mM)r |
| Water: 33 mg/mL (26.5 mM)r | |
| Ethanol: 100 mg/mL (80.4 mM) | |
| Solubility In Vivo | Chemical Name: benzenesulfonate;5-[3-[1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-2-ium-2-yl]propanoyloxy]pentyl 3-[1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-2-ium-2-yl]propanoate InChi Key: KTFFUISFKXNFHH-UHFFFAOYSA-N InChi Code: InChI=1S/C53H72N2O12.C6H6O3S/c1-12-13-14-27-66-50(56)21-25-55(3)24-20-38-40(42(55)29-36-16-18-44(59-5)46(31-36)61-7)34-49(64-10)53(65-11)52(38)67-51(57)22-26-54(2)23-19-37-32-47(62-8)48(63-9)33-39(37)41(54)28-35-15-17-43(58-4)45(30-35)60-6;7-10(8,9)6-4-2-1-3-5-6/h15-18,30-34,41-42H,12-14,19-29H2,1-11H3;1-5H,(H,7,8,9)/q+2; SMILES Code: O=C(OCCCCC)CC[N+]1(C)C(CC2=CC=C(OC)C(OC)=C2)C3=C(C(OC(CC[N+]4(C)C(CC5=CC=C(OC)C(OC)=C5)C6=C(C=C(OC)C(OC)=C6)CC4)=O)=C(OC)C(OC)=C3)CC1.O=S(C7=CC=CC=C7)(O)=O |
| Synonyms | BW 33 A; 51W89; Atracurium Dibesylate; BW 33A; BW-33A; BW33A; Relatrac; Tracrium |
| Protocol | In Vitro | Atracurium besylate (2.4 µM; 120 min) induces a complete fade of the tetanic contraction while only slightly affected the twitch in rat extensor digitorum longus muscle cells |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 0.8042 mL | 4.0210 mL | 8.0419 mL | 16.0839 mL |
| 5mM | 0.1608 mL | 0.8042 mL | 1.6084 mL | 3.2168 mL |
| 10mM | 0.0804 mL | 0.4021 mL | 0.8042 mL | 1.6084 mL |
| 20mM | 0.0402 mL | 0.2010 mL | 0.4021 mL | 0.8042 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.