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Bupivacaine (SKY 0402)

This product is for research use only, not for human use. We do not sell to patients.

Bupivacaine (SKY 0402)
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
5g$450Check With Us
10g$650Check With Us
20g$975Check With Us

Cat #: V17217 CAS #: 38396-39-3 Purity ≥ 98%

Description: Bupivacaine (AH-250; HSDB 7790; SKY 0402) is a BK/SK, Kv1, Kv3, TASK-2 K Channel and voltage-gated Na channel blocker used as an anesthetic.

References: Meaghan A Paganelli, et al. Actions of Bupivacaine, a widely used local anesthetic, on NMDA receptor responses. J Neurosci. 2015 Jan 14;35(2):831-42.

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Product Promise

Promise
Molecular Weight (MW)288.43
Molecular FormulaC18H28N2O
CAS No.38396-39-3
ProtocolIn VitroBupivacaine inhibits NMDA receptor-mediated synaptic transmission in the dorsal horn of the spinal cord, an area critically involved in central sensitization
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM3.4670 mL17.3352 mL34.6705 mL69.3409 mL
5mM0.6934 mL3.4670 mL6.9341 mL13.8682 mL
10mM0.3467 mL1.7335 mL3.4670 mL6.9341 mL
20mM0.1734 mL0.8668 mL1.7335 mL3.4670 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.