CNQX Disodium

This product is for research use only, not for human use. We do not sell to patients.

CNQX Disodium
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Size Price Stock
250mg$450Check With Us
500mg$750Check With Us
1g$1125Check With Us

Cat #: V18479 CAS #: 479347-85-8 Purity ≥ 98%

Description: CNQX Disodium (FG-9065), the disodium salt form of CNQX, is a potent AMPA/kainate antagonist with higher water-solubility than the free acid form CNQX (Cat. No. V33762).

References: Pia Bäckström, et al. Attenuation of Cocaine-Seeking Behaviour by the AMPA/kainate Receptor Antagonist CNQX in Rats. Psychopharmacology (Berl). 2003 Feb;166(1):69-76.

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Product Promise

Promise
Molecular Weight (MW)276.11
Molecular FormulaC9H2N4Na2O4
CAS No.479347-85-8
Synonyms FG9065; FG-9065
ProtocolIn VivoCNQX disodium (FG9065 disodium; 0.75-3 mg/kg; IP; 20 min before testing) decreased the number of cocaine responses in a dose-dependent manner during the first 15-min cocaine-free interval
Animal modelMale Wistar rats weighing 180-200 g
Dosages0.75, 1.5, and 3 mg/kg
AdministrationIP; 20 min before testing
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM3.6217 mL18.1087 mL36.2174 mL72.4349 mL
5mM0.7243 mL3.6217 mL7.2435 mL14.4870 mL
10mM0.3622 mL1.8109 mL3.6217 mL7.2435 mL
20mM0.1811 mL0.9054 mL1.8109 mL3.6217 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
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Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.