SYM2206

This product is for research use only, not for human use. We do not sell to patients.

SYM2206
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$1540Check With Us
500mg$2550Check With Us
1g$3825Check With Us

Cat #: V2970 CAS #: 173952-44-8 Purity ≥ 98%

Description: SYM2206 is a potent, specific and non-competitive antagonist of AMPA (α-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid receptor) receptors with IC50 value of 2.8 μM.

References: Bleakman D, et, al. Kainate receptor agonists, antagonists and allosteric modulators. Curr Pharm Des. 2002;8(10):873-85.

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Product Promise

Promise
Molecular Weight (MW)366.41
Molecular FormulaC20H22N4O3
CAS No.173952-44-8
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 10 mMr
Water: <1 mg/mLr
Ethanol: <1 mg/mL
SynonymsSYM2206; SYM 2206; SYM-2206
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.7292 mL13.6459 mL27.2918 mL54.5837 mL
5mM0.5458 mL2.7292 mL5.4584 mL10.9167 mL
10mM0.2729 mL1.3646 mL2.7292 mL5.4584 mL
20mM0.1365 mL0.6823 mL1.3646 mL2.7292 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.