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MK-571 (L660711)

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MK-571 (L660711)
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Size Price Stock
100mg$750Check With Us
250mg$1400Check With Us
500mg$2100Check With Us
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Cat #: V40891 CAS #: 115104-28-4 Purity ≥ 99%

Description: MK-571 (L-660711) is a novel, potent, selective, orally bioactive antagonist of leukotriene D4 (LTD4) receptor with Kis of 0.22 and 2.1 nM in guinea pig and human lung membranes.

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Molecular Weight (MW)515
Molecular FormulaC26H27ClN2O3S2
CAS No.115104-28-4
SMILES CodeClC1=CC=C(C=CC(/C=C/C3=CC(C(SCCC(O)=O)SCCC(N(C)C)=O)=CC=C3)=N2)C2=C1
SynonymsMK-571; MK 571; MK571; MK-571; L-660,711; L660,711; L 660,711; L-660711; L660711; L 660711;
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.9417 mL9.7087 mL19.4175 mL38.8350 mL
5mM0.3883 mL1.9417 mL3.8835 mL7.7670 mL
10mM0.1942 mL0.9709 mL1.9417 mL3.8835 mL
20mM0.0971 mL0.4854 mL0.9709 mL1.9417 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
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The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

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Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.