MK571(L660711)

This product is for research use only, not for human use. We do not sell to patients.

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Size	Price	Stock
100mg	$480	Check With Us
250mg	$800	Check With Us
500mg	$1200	Check With Us

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Cat #: V2405 CAS #: 115104-28-4 Purity ≥ 99%

Description: MK571, also known as L660711, is a potent and selective competitive inhibitor of [3H]leukotriene D4 binding in guinea pig (Ki value, 0.22 nM) and human (Ki value, 2.1 nM) lung membranes but is essentially inactive versus [3H]leukotriene C4 binding (IC50 value in guinea pig lung, 23 microM).

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Molecular Weight (MW)	515.08
Molecular Formula	C26H27ClN2O3S2
CAS No.	115104-28-4
SMILES Code	CN(C)C(=O)CCSC(SCCC(=O)O)c1cccc(\C=C\c2ccc3ccc(Cl)cc3n2)c
Synonyms	MK 571; MK571; MK-571; Verlukast; L 660,711; L 660711; L660711; L-660711; MK 0571; MK0571; MK-0571;

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	1.9414 mL	9.7072 mL	19.4145 mL	38.8289 mL
5mM	0.3883 mL	1.9414 mL	3.8829 mL	7.7658 mL
10mM	0.1941 mL	0.9707 mL	1.9414 mL	3.8829 mL
20mM	0.0971 mL	0.4854 mL	0.9707 mL	1.9414 mL

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.