Nisoldipine

This product is for research use only, not for human use. We do not sell to patients.

Nisoldipine
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
2g$180Check With Us
5g$320Check With Us
10g$480Check With Us

Cat #: V0920 CAS #: 63675-72-9 Purity ≥ 98%

Description: Nisoldipine (BAY-K-5552; Bay K-5552, Sular, Baymycard, Nisocor, Syscor) is a novel CCB-calcium channel blocker of the dihydropyridine (DHP) class with vasodilating and antihypertensive effects.

References: Hamilton SF, Houle LM, Thadani U. Rapid-release and coat-core formulations of nisoldipine in treatment of hypertension, angina, and heart failure. Heart Dis. 1999 Nov-Dec;1(5):279-88.

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Product Promise

Promise
Molecular Weight (MW)388.41
Molecular FormulaC20H24N2O6
CAS No.63675-72-9
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 77 mg/mL (198.2 mM)r
Water: <1 mg/mLr
Ethanol: 60 mg/mL (154.5 mM)
SynonymsBAY K 5552; Bay K-5552, Sular, Baymycard, BAY-K-5552; Nisoldipine, Nisocor, Syscor
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.5746 mL12.8730 mL25.7460 mL51.4920 mL
5mM0.5149 mL2.5746 mL5.1492 mL10.2984 mL
10mM0.2575 mL1.2873 mL2.5746 mL5.1492 mL
20mM0.1287 mL0.6436 mL1.2873 mL2.5746 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.