Prednisolone
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 50g | $450 | Check With Us |
| 100g | $650 | Check With Us |
| 200g | $975 | Check With Us |
: Cat #: V1698 CAS #: 50-24-8 Purity ≥ 98%
Description: Prednisolone (AKOS-016010152; AK-115681; Predsol; Pediapred) is an approved medication acting as a potent and synthetic glucocorticoid with anti-inflammatory and immunomodulatory properties.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 360.44 |
|---|---|
| Molecular Formula | C21H28O5 |
| CAS No. | 50-24-8 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 72 mg/mL (199.7 mM)r |
| Water:<1 mg/mLr | |
| Ethanol: 10 mg/mL (27.7 mM) | |
| Synonyms | AKOS016010152; AK115681; AKOS 016010152; AK 115681; AKOS-016010152; AK-115681; sodium phosphate Predsol; Pediapred |
| Protocol | In Vivo | Prednisolone (5 mg/kg/day; p.o.; 6 days a week for 72 weeks) significantly prevents deaths from renal disease in mice |
|---|---|---|
| Animal model | NZB/NZW mice, immune nephritis model | |
| Dosages | 5 mg/kg/day | |
| Administration | Oral, 6 days a week for 72 weeks |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.7744 mL | 13.8719 mL | 27.7439 mL | 55.4877 mL |
| 5mM | 0.5549 mL | 2.7744 mL | 5.5488 mL | 11.0975 mL |
| 10mM | 0.2774 mL | 1.3872 mL | 2.7744 mL | 5.5488 mL |
| 20mM | 0.1387 mL | 0.6936 mL | 1.3872 mL | 2.7744 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.