Fluocinonide (Vanos)

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
2g	$200	Check With Us
10g	$600	Check With Us
20g	$900	Check With Us

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Cat #: V1707 CAS #: 356-12-7 Purity ≥ 98%

Description: Fluocinonide (Lidex, Lyderm, Metosyn, Topsyn, Fluocinolide, Vanos, Lonide) is a potent glucocorticoid/corticosteroid that has been approved for use as a topical anti-inflammatory drug for the treatment of skin disorders such as seborrhoeic dermatitis and eczema.

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Physicochemical and Storage Information
Protocol
Related Biological Data
Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	494.52
Molecular Formula	C26H32F2O7
CAS No.	356-12-7
Storage	-20℃ for 3 years in powder formr
Storage	-80℃ for 2 years in solvent
Solubility In Vitro	DMSO: 99 mg/mL (200.2 mM)r
	Water: <1 mg/mLr
	Ethanol: N/A
Synonyms	Lidex, Lyderm, Metosyn, Topsyn, Fluocinolide, Vanos, Lonide

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	2.0222 mL	10.1108 mL	20.2216 mL	40.4433 mL
5mM	0.4044 mL	2.0222 mL	4.0443 mL	8.0887 mL
10mM	0.2022 mL	1.0111 mL	2.0222 mL	4.0443 mL
20mM	0.1011 mL	0.5055 mL	1.0111 mL	2.0222 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.