Amlodipine maleate
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 10g | $450 | Check With Us |
| 25g | $650 | Check With Us |
| 50g | $975 | Check With Us |
: Cat #: V28956 CAS #: 88150-47-4 Purity ≥ 99%
Description: Amlodipine maleate (Amvaz; Norvasc), the maleate salt of Amlodipine, is an antihypertensive medication of the dihydropyridine (DHP) class used for lowering blood pressure, angina pectoris and preventing chest pain.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
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| Molecular Weight (MW) | 524.95 |
|---|---|
| Molecular Formula | C₂₄H₂₉ClN₂O₉ |
| CAS No. | 88150-47-4 |
| SMILES Code | C=1([C@@H](C(=C(NC1COCCN)C)C(OC)=O)c1c(cccc1)Cl)C(OCC)=O.OC(C=C/C(O)=O)=O |
| Synonyms | Amlodipine (+-)-form maleate, Amvaz |
| Protocol | In Vitro | Amlodipine maleate (20-40 μM; 48 h) reduces BrdU incorporation to 68.6% and 26.3% at concentrations of 20 and 30 μM in A431 cells, respectively. |
|---|---|---|
| In Vivo | Amlodipine maleate (10 mg/kg; i.p. once daily for 20 days) causes a significant retardation of tumor growth and prolongs the survival of A431 tumor-bearing mice. |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 1.9049 mL | 9.5247 mL | 19.0494 mL | 38.0989 mL |
| 5mM | 0.3810 mL | 1.9049 mL | 3.8099 mL | 7.6198 mL |
| 10mM | 0.1905 mL | 0.9525 mL | 1.9049 mL | 3.8099 mL |
| 20mM | 0.0952 mL | 0.4762 mL | 0.9525 mL | 1.9049 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.