Benidipine HCl

This product is for research use only, not for human use. We do not sell to patients.

Benidipine HCl
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
1g$550Check With Us
2g$950Check With Us
5g$1550Check With Us

Cat #: V0885 CAS #: 91599-74-5 Purity ≥ 98%

Description: Benidipine HCl (formerly SC-278724, KW-3049 HCl; trade names Sular; Coniel) is the hydrochloride salt form of benidipine which is a DHP/dihydropyridine calcium channel blocker/CCB with anti-hypertensive activity.

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Product Promise

Promise
Molecular Weight (MW)542.02
Molecular FormulaC28H31N3O6.HCl
CAS No.91599-74-5
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 8 mg/mL (14.8 mM)r
Water: <1 mg/mLr
Ethanol: <1 mg/mL
Solubility In VivoChemical Name: 3-((R)-1-benzylpiperidin-3-yl) 5-methyl (R)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate hydrochloride InChi Key: KILKDKRQBYMKQX-MIPPOABVSA-N InChi Code: InChI=1S/C28H31N3O6.ClH/c1-18-24(27(32)36-3)26(21-11-7-12-22(15-21)31(34)35)25(19(2)29-18)28(33)37-23-13-8-14-30(17-23)16-20-9-5-4-6-10-20;/h4-7,9-12,15,23,26,29H,8,13-14,16-17H2,1-3H3;1H/t23-,26-;/m1./s1 SMILES Code: O=C(C1=C(C)NC(C)=C(C(O[C@H]2CN(CC3=CC=CC=C3)CCC2)=O)[C@@H]1C4=CC=CC([N+]([O-])=O)=C4)OC.[H]Cl
SynonymsKW-3049; KW3049; Coniel; Benidipine Hydrochloride; KW 3049;
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.8450 mL9.2248 mL18.4495 mL36.8990 mL
5mM0.3690 mL1.8450 mL3.6899 mL7.3798 mL
10mM0.1845 mL0.9225 mL1.8450 mL3.6899 mL
20mM0.0922 mL0.4612 mL0.9225 mL1.8450 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.