HPGDS inhibitor 2
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
Size | Price | Stock |
---|---|---|
250mg | $1350 | Check With Us |
500mg | $2350 | Check With Us |
1g | $3525 | Check With Us |
Cat #: V31708 CAS #: 2101626-26-8 Purity ≥ 99%
Description: HPGDS inhibitor 2 (GSK2894631A) is a novel, potent, highly potent and selective hematopoietic prostaglandin D synthase (H-PGDS) inhibitor with an IC50 of 9.9 nM.
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Molecular Weight (MW) | 378.41 |
---|---|
Molecular Formula | C20H24F2N2O3 |
CAS No. | 2101626-26-8 |
SMILES Code | O=C(C1=CC2=CC=C(OC(F)F)C=C2N=C1)N[C@H]3CC[C@H](C(C)(O)C)CC3 |
Synonyms | GSK 2894631A; GSK2894631; GSK-2894631; GSK 2894631; GSK2894631A; GSK-2894631A; |
Solvent volume to be added | Mass (the weight of a compound) | |||
---|---|---|---|---|
Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
1mM | 2.6426 mL | 13.2132 mL | 26.4264 mL | 52.8527 mL |
5mM | 0.5285 mL | 2.6426 mL | 5.2853 mL | 10.5705 mL |
10mM | 0.2643 mL | 1.3213 mL | 2.6426 mL | 5.2853 mL |
20mM | 0.1321 mL | 0.6607 mL | 1.3213 mL | 2.6426 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
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Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
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Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
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Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.