NS-5806
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 100mg | $850 | To Be Confirmed |
| 250mg | $1750 | To Be Confirmed |
| 500mg | $2625 | To Be Confirmed |
: Cat #: V21754 CAS #: 426834-69-7 Purity ≥ 99%
Description: NS-5806 (NS5806) is a novel and potent potassium current KV4.3 channel activator which increases KV4.3/KChIP2 peak current amplitudes with an EC50 of 5.3 μM.
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| Molecular Weight (MW) | 574.07 |
|---|---|
| Molecular Formula | C16H8Br2F6N6O |
| CAS No. | 426834-69-7 |
| Synonyms | NS5806; NS 5806 |
| Protocol | In Vitro | NS5806 (10 µM) induces a 65% increase of KV4.3/KChIP2/DPP6 peak current amplitudes concentration-dependently and the time course of inactivation (τ) is slowed with an EC50 value of 25.4 µM in CHO-K1 cells |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 1.7419 mL | 8.7097 mL | 17.4195 mL | 34.8390 mL |
| 5mM | 0.3484 mL | 1.7419 mL | 3.4839 mL | 6.9678 mL |
| 10mM | 0.1742 mL | 0.8710 mL | 1.7419 mL | 3.4839 mL |
| 20mM | 0.0871 mL | 0.4355 mL | 0.8710 mL | 1.7419 mL |
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The dilution calculator equation
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Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.