Cortisone
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 2g | $300 | Check With Us |
| 5g | $480 | Check With Us |
| 10g | $720 | Check With Us |
: Cat #: V8386 CAS #: 53-06-5 Purity ≥ 98%
Description: Cortisone is a potent and naturally occurring glucocorticoid with anti-inflammatory activities.
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- Physicochemical and Storage Information
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- Related Biological Data
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| Molecular Weight (MW) | 360.44 |
|---|---|
| Molecular Formula | C21H28O5 |
| CAS No. | 53-06-5 |
| SMILES Code | C[C@@]1(C2)[C@](C(CO)=O)(O)CC[C@@]1([H])[C@]3([H])CCC4=CC(CC[C@]4(C)[C@@]3([H])C2=O)=O |
| Synonyms | Cortisone; NSC 9703; NSC9703; NSC-9703; |
| Protocol | In Vitro | Cortisone (2.8-28,000 nM) dose-dependently attenuates the apoptosis induced by Cortisol in peripheral-blood mononuclear cells (PBMCs). |
|---|---|---|
| In Vivo | Cortisone (2 mg/kg; i.m. on alternate days for 2 months) decreases the BCG (the vaccine strain of tubercle bacillus) lesions and tuberculin reactions in rabbits. |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.7744 mL | 13.8719 mL | 27.7439 mL | 55.4877 mL |
| 5mM | 0.5549 mL | 2.7744 mL | 5.5488 mL | 11.0975 mL |
| 10mM | 0.2774 mL | 1.3872 mL | 2.7744 mL | 5.5488 mL |
| 20mM | 0.1387 mL | 0.6936 mL | 1.3872 mL | 2.7744 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.