Esomeprazole Magnesium | Omeprazole magnesium | Nexium"/>
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Esomeprazole Magnesium trihydrate

This product is for research use only, not for human use. We do not sell to patients.

Esomeprazole Magnesium trihydrate
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
1g$650Check With Us
2g$980Check With Us
5g$1550Check With Us
email: [email protected]        [email protected]

Cat #: V31594 CAS #: 217087-09-7 Purity ≥ 99%

Description: Esomeprazole Magnesium trihydrate (S-Omeprazole magnesium trihydrate) is a proton pump inhibitor (PPI) that is used to reduce gastric acid secretion.

References: Pankaj Kumar, et al. Preparation and characterization of pH-sensitive methyl methacrylate-g-starch/hydroxypropylated starch hydrogels: in vitro and in vivo study on release of esomeprazole magnesium. Drug Deliv Transl Res. 2015 Jun;5(3):243-56.

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Molecular Weight (MW)767.17
Molecular FormulaC₃₄H₄₂MgN₆O₉S₂
CAS No.217087-09-7
SynonymsS-Omeprazole magnesium trihydrate; <span id="xn_c_prodv_37_conT1_t">Esomeprazole Magnesium; Omeprazole magnesium; Nexium
ProtocolIn VitroEsomeprazole magnesium trihydrate is develped from Esomeprazole strontium tetrahydrate (EST). EST contains esomeprazole, the S-enantiomer of omeprazole a salt-exchanged version of Esomeprazole magnesium trihydrate
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.3035 mL6.5175 mL13.0349 mL26.0698 mL
5mM0.2607 mL1.3035 mL2.6070 mL5.2140 mL
10mM0.1303 mL0.6517 mL1.3035 mL2.6070 mL
20mM0.0652 mL0.3259 mL0.6517 mL1.3035 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
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The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
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Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.