Dyngo-4a
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 250mg | $480 | Check With Us |
| 500mg | $829 | Check With Us |
| 1g | $1240 | Check With Us |
: Cat #: V1592 CAS #: 1256493-34-1 Purity ≥ 98%
Description: Dyngo-4a (Dyngo 4a; Hydroxy Dynasore) is a potent and novel dynamin inhibitor with the potential to treat botulism.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 338.31 |
|---|---|
| Molecular Formula | C18H14N2O5 |
| CAS No. | 1256493-34-1 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 67 mg/mL (198.0 mM)r |
| Water: <1 mg/mLr | |
| Ethanol: <1 mg/mL | |
| Synonyms | Dyngo-4a; Dyngo 4a; Hydroxy Dynasore; Dyngo4a; |
| Protocol | In Vitro | Kinein is a large GTPase that cuts membrane-bound clathrin-coated vesicles. Endocytosis, which internalizes part of the cytoplasmic membrane along with extracellular material, is of fundamental importance in cell physiology. Hydroxy Dynasore inhibits dynein I (Dyn I) activity, IC50 Values of 2.7 μM and 0.38 μM with or without 0.06% Tween-80 were determined in GTPase |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.9559 mL | 14.7793 mL | 29.5587 mL | 59.1174 mL |
| 5mM | 0.5912 mL | 2.9559 mL | 5.9117 mL | 11.8235 mL |
| 10mM | 0.2956 mL | 1.4779 mL | 2.9559 mL | 5.9117 mL |
| 20mM | 0.1478 mL | 0.7390 mL | 1.4779 mL | 2.9559 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.