This product is for research use only, not for human use. We do not sell to patients.
| Size | Price | Stock |
|---|---|---|
| 250mg | $800 | Check With Us |
| 500mg | $1280 | Check With Us |
| 1g | $1920 | Check With Us |
: Cat #: V1590 CAS #: 304448-55-3 Purity ≥ 98%
Description: Dynasore is a cell-permeable, reversible and non-competitive dynamin inhibitor of GTPase activity of dynamin 1/2 (IC50 = 15 μM) with cardioprotective effects.
References: Macia E, et al. Dynasore, a cell-permeable inhibitor of dynamin. Dev Cell. 2006 Jun;10(6):839-50.
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| Molecular Weight (MW) | 322.31 |
|---|---|
| Molecular Formula | C18H14N2O4 |
| CAS No. | 304448-55-3 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 64 mg/mL (198.6 mM)r |
| Water: <1 mg/mLr | |
| Ethanol: <1 mg/mL | |
| Synonyms | Dynasore |
| Protocol | In Vivo | Dynasore ameliorates the motor dysfunction greatly at 3, 7, and 10 days after SCI in rats. Dynasore significantly enhances motor function which may be by inhibiting the activation of neuronal mitochondrial apoptotic pathway and astrocytic proliferation in rats after SCI |
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| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 3.1026 mL | 15.5130 mL | 31.0260 mL | 62.0521 mL |
| 5mM | 0.6205 mL | 3.1026 mL | 6.2052 mL | 12.4104 mL |
| 10mM | 0.3103 mL | 1.5513 mL | 3.1026 mL | 6.2052 mL |
| 20mM | 0.1551 mL | 0.7757 mL | 1.5513 mL | 3.1026 mL |
This equation is commonly abbreviated as: C1 V1 = C2 V2
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.