JBSNF-000088

This product is for research use only, not for human use. We do not sell to patients.

JBSNF-000088
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
2g$400Check With Us
5g$700Check With Us
10g$1050Check With Us

Cat #: V22863 CAS #: 7150-23-4 Purity ≥ 98%

Description: JBSNF-000088 (JBSNF 000088; JBSNF000088), a nicotinamide analog, is a potent inhibitor of Nicotinamide N-methyltransferase (NNMT) with the potential to treat metabolic disorders such as obesity.

References: Kannt A, et al. A small molecule inhibitor of Nicotinamide N-methyltransferase for the treatment of metabolic disorders. Sci Rep. 2018 Feb 26;8(1):3660.

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Product Promise

Promise
Molecular Weight (MW)152.15
Molecular FormulaC7H8N2O2
CAS No.7150-23-4
SMILES CodeO=C(N)C1=CN=C(OC)C=C1
SynonymsJBSNF-000088; JBSNF 000088; JBSNF000088
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM6.5725 mL32.8623 mL65.7246 mL131.4492 mL
5mM1.3145 mL6.5725 mL13.1449 mL26.2898 mL
10mM0.6572 mL3.2862 mL6.5725 mL13.1449 mL
20mM0.3286 mL1.6431 mL3.2862 mL6.5725 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.