NSC228155
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 250mg | $750 | To Be Confirmed |
| 500mg | $1150 | To Be Confirmed |
| 1g | $1725 | To Be Confirmed |
: Cat #: V2675 CAS #: 113104-25-9 Purity ≥ 98%
Description: NSC228155 is a novel and potent activator of EGFR, which binds to the sEGFR dimerization domain II and modulate EGFR tyrosine phosphorylation.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 290.25 |
|---|---|
| Molecular Formula | C11H6N4O4S |
| CAS No. | 113104-25-9 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 58 mg/mL (199.8 mM)r |
| Water: <1 mg/mLr | |
| Ethanol: <1 mg/mL | |
| SMILES Code | O=[N+](C1=CC=C(SC2=CC=CC=[N+]2[O-])C3=NON=C31)[O-] |
| Synonyms | NSC228155; NSC-228155; NSC 228155 |
| Protocol | In Vitro | NSC 228155 (100 μM) enhances EGFR tyrosine phosphorylation via action of SOD1. |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 3.4453 mL | 17.2265 mL | 34.4531 mL | 68.9061 mL |
| 5mM | 0.6891 mL | 3.4453 mL | 6.8906 mL | 13.7812 mL |
| 10mM | 0.3445 mL | 1.7227 mL | 3.4453 mL | 6.8906 mL |
| 20mM | 0.1723 mL | 0.8613 mL | 1.7227 mL | 3.4453 mL |
The molarity calculator equation
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The dilution calculator equation
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This equation is commonly abbreviated as: C1 V1 = C2 V2
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Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.