Ropsacitinib (PF-06826647; Tyk2-IN-8)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 25mg | $1050 | Check With Us |
| 50mg | $1650 | Check With Us |
| 1g | $2475 | Check With Us |
: Cat #: V31670 CAS #: 2127109-84-4 Purity ≥ 99%
Description: Ropsacitinib (PF-06826647; Tyk2-IN-8; PF06826647) is a novel, selective and orally bioavailable TYK2 (tyrosine kinase) inhibitor with potential anti-inflammatory activity.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 383.419 |
|---|---|
| Molecular Formula | C20H17N9 |
| CAS No. | 2127109-84-4 |
| SMILES Code | N#C[C@@H]1C[C@@](CC#N)(N2N=CC(C3=NC(C4=CN(C)N=C4)=CN5N=CC=C35)=C2)C1 |
| Synonyms | PF-06826647; PF 06826647; PF06826647; PF-6826647; PF 6826647; PF6826647; Tyk2-IN-8; Tyk2-IN 8; Tyk2-IN8; Ropsacitini |
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.6081 mL | 13.0406 mL | 26.0811 mL | 52.1623 mL |
| 5mM | 0.5216 mL | 2.6081 mL | 5.2162 mL | 10.4325 mL |
| 10mM | 0.2608 mL | 1.3041 mL | 2.6081 mL | 5.2162 mL |
| 20mM | 0.1304 mL | 0.6520 mL | 1.3041 mL | 2.6081 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.