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Oltipraz (RP 35972; NSC 347901)

This product is for research use only, not for human use. We do not sell to patients.

Oltipraz (RP 35972; NSC 347901)
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
500mg$280Check With Us
1g$470Check With Us
5g$705Check With Us

Cat #: V1892 CAS #: 64224-21-1 Purity ≥ 98%

Description: Oltipraz (RP 35972; NSC 347901), a potential anticancer agent, is a potent Nrf2 activator and an inducer of Phase II detoxification enzymes such as glutathione-S-transferase (GST).

References: Lee WH, et al. Oltipraz and dithiolethione congeners inhibit hypoxia-inducible factor-1alpha activity through p70 ribosomal S6 kinase-1 inhibition and H2O2-scavenging effect. Mol Cancer Ther. 2009 Oct;8(10):2791-802.

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Product Promise

Promise
Molecular Weight (MW)226.34
Molecular FormulaC8H6N2S3
CAS No.64224-21-1
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 39 mg/mL (172.3 mM)r
Water: <1 mg/mLr
Ethanol: <1 mg/mL
SMILES CodeS=C1SSC(C2=NC=CN=C2)=C1C
SynonymsCD-1400; CD1400; CD 1400
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM4.4181 mL22.0907 mL44.1813 mL88.3626 mL
5mM0.8836 mL4.4181 mL8.8363 mL17.6725 mL
10mM0.4418 mL2.2091 mL4.4181 mL8.8363 mL
20mM0.2209 mL1.1045 mL2.2091 mL4.4181 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.