Methyl 3,4-dihydroxybenzoate
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 1g | $380 | Check With Us |
| 2g | $650 | Check With Us |
| 5g | $1095 | Check With Us |
: Cat #: V31615 CAS #: 2150-43-8 Purity ≥ 99%
Description: Methyl 3,4-dihydroxybenzoate is a novel and potent metabolite of antioxidant polyphenol.
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| Molecular Weight (MW) | 168.15 |
|---|---|
| Molecular Formula | C8H8O4 |
| CAS No. | 2150-43-8 |
| Synonyms | Protocatechuic acid methyl ester; |
| Protocol | In Vitro | Methyl 3,4-dihydroxybenzoate (Protocatechuic acid methyl ester; Methyl protocatechuate) alleviates the toxic effects of F- via modulating its bioavailability, intracellular calcium level, mitochondrial membrane integrity and redox signaling in A549 cells. |
|---|---|---|
| In Vivo | Methyl 3,4-dihydroxybenzoate (Protocatechuic acid methyl ester; Methyl protocatechuate) (25 or 50 mg/kg bw/day) prevents the cellular F- accumulation and oxidative stress. Methyl 3,4-dihydroxybenzoate prevents the inflammatory and associated fibrosis progression by restoring the expression of RAGE and Nrf2. |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 5.9471 mL | 29.7354 mL | 59.4707 mL | 118.9414 mL |
| 5mM | 1.1894 mL | 5.9471 mL | 11.8941 mL | 23.7883 mL |
| 10mM | 0.5947 mL | 2.9735 mL | 5.9471 mL | 11.8941 mL |
| 20mM | 0.2974 mL | 1.4868 mL | 2.9735 mL | 5.9471 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.