Rotenone

This product is for research use only, not for human use. We do not sell to patients.

Rotenone
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
10g$165Check With Us
25g$300Check With Us
50g$450Check With Us

Cat #: V11545 CAS #: 83-79-4 Purity ≥ 99%

Description: Rotenone is a potent botanical insecticide which acts as an inhibitor of mitochondrial electron transport chain complex I.

References: Khadrawy YA, et al. Cerebellar neurochemical and histopathological changes in rat model of Parkinson's disease induced by intrastriatal injection of rotenone. Gen Physiol Biophys. 2016 Nov 30.

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Molecular Weight (MW)394.42
Molecular FormulaC23H22O6
CAS No.83-79-4
SMILES CodeO=C1C2C(COC3=CC(OC)=C(OC)C=C32)OC4=C1C=CC5=C4CC(C(C)=C)O5 
SynonymsRotenone; Cube root; bCube-Pulver; Ronone; HSDB 1762; Ro-KO;
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.5354 mL12.6768 mL25.3537 mL50.7074 mL
5mM0.5071 mL2.5354 mL5.0707 mL10.1415 mL
10mM0.2535 mL1.2677 mL2.5354 mL5.0707 mL
20mM0.1268 mL0.6338 mL1.2677 mL2.5354 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.