WS6

This product is for research use only, not for human use. We do not sell to patients.

WS6
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$900Check With Us
500mg$1350Check With Us
1g$2025Check With Us

Cat #: V0759 CAS #: 1421227-53-3 Purity ≥ 98%

Description: WS6 (WS6; WS 6) is a novel and potent small molecule modulator of β cell proliferation via modulation of Erb3 binding protein-1 (EBP1) and the IκB kinase pathway with important biological activity.

References: Shen W, et al. Small-molecule inducer of β cell proliferation identified by high-throughput screening. J Am Chem Soc. 2013 Feb 6;135(5):1669-72.

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Product Promise

Promise
Molecular Weight (MW)568.59
Molecular FormulaC29H31F3N6O3
CAS No.1421227-53-3
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 100 mg/mL (175.9 mM)r
Water: <1 mg/mLr
Ethanol: 100 mg/mL (175.9 mM)
SMILES CodeO=C(NC1=CC=C(CN2CCN(C)CC2)C(C(F)(F)F)=C1)CC3=CC=C(OC4=NC=NC(NC(C5CC5)=O)=C4)C=C3
SynonymsWS-6; WS 6; WS6;
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.7587 mL8.7937 mL17.5874 mL35.1747 mL
5mM0.3517 mL1.7587 mL3.5175 mL7.0349 mL
10mM0.1759 mL0.8794 mL1.7587 mL3.5175 mL
20mM0.0879 mL0.4397 mL0.8794 mL1.7587 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.