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Chrysophanic Acid (Chrysophanol)

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Chrysophanic Acid (Chrysophanol)
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
1g$220Check With Us
2g$400Check With Us
5g$675Check With Us

Cat #: V0207 CAS #: 481-74-3 Purity ≥ 98%

Description: Chrysophanic acid (also called Chrysophanol), a naturally occuring anthraquinone isolated from Dianella longifolia, is a selective and potent inhibitor of EGFR/mTOR (epidermal growth factor (EGF) receptor/mammalian target of rapamycin) with potential anti-obesity and antitumor activity.

References: Lee MS, et al. Chrysophanic acid blocks proliferation of colon cancer cells by inhibiting EGFR/mTOR pathway. Phytother Res. 2011 Jun;25(6):833-7.

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Product Promise

Promise
Molecular Weight (MW)254.24
Molecular FormulaC15H10O4
CAS No.481-74-3
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 5 mg/mL (19.66 mM)r
Water: <1 mg/mLr
Ethanol: <1 mg/mL
SMILES CodeO=C1C2=C(C=CC=C2O)C(C3=CC(C)=CC(O)=C13)=O
SynonymsChrysophanic acid; Chrysophanol
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM3.9333 mL19.6665 mL39.3329 mL78.6658 mL
5mM0.7867 mL3.9333 mL7.8666 mL15.7332 mL
10mM0.3933 mL1.9666 mL3.9333 mL7.8666 mL
20mM0.1967 mL0.9833 mL1.9666 mL3.9333 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.