SKLB610

This product is for research use only, not for human use. We do not sell to patients.

SKLB610
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$750Check With Us
500mg$1250Check With Us
1g$1875Check With Us

Cat #: V2879 CAS #: 1125780-41-7 Purity ≥ 99%

Description: SKLB610 is a novel multi-targeted kinase inhibitor with more potent inhibition of VEGFR2.

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Product Promise

Promise
Molecular Weight (MW)415.37
Molecular FormulaC21H16F3N3O3
CAS No.1125780-41-7
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 10mMr
Water: <1 mg/mL
SMILES CodeO=C(NC)C1=NC=CC(OC2=CC=C(NC(C3=CC=CC(C(F)(F)F)=C3)=O)C=C2)=C1
SynonymsSKLB610; SKLB 610; SKLB-610.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.4075 mL12.0375 mL24.0749 mL48.1498 mL
5mM0.4815 mL2.4075 mL4.8150 mL9.6300 mL
10mM0.2407 mL1.2037 mL2.4075 mL4.8150 mL
20mM0.1204 mL0.6019 mL1.2037 mL2.4075 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.