SAR348830

This product is for research use only, not for human use. We do not sell to patients.

SAR348830
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$1250Check With Us
500mg$1850Check With Us
1g$2775Check With Us

Cat #: V14334 CAS #: 1462949-64-9 Purity ≥ 98%

Description: SAR348830 (SAR-348830; SAR 348830) is potent and selective inhibitor of anaplastic lymphoma kinase (ALK ) with the potential to be used for treating Non-small Cell Lung Cancer.

References: Carry JC, et, al. Novel thienopyrimidine derivatives, processes for the preparation thereof and therapeutic uses thereof. US20130261106A1.

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Product Promise

Promise
Molecular Weight (MW)537.65
Molecular FormulaC28H32FN5O3S
CAS No.1462949-64-9
SMILES CodeOCC1=C(C2=CC(F)=CC=C2OC)C3=NC(NC4=CC=C(N5CCN(C)CC5)C=C4OC(C)C)=NC=C3S1
SynonymsSAR348830; SAR 348830; SAR-348830
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.8599 mL9.2997 mL18.5995 mL37.1989 mL
5mM0.3720 mL1.8599 mL3.7199 mL7.4398 mL
10mM0.1860 mL0.9300 mL1.8599 mL3.7199 mL
20mM0.0930 mL0.4650 mL0.9300 mL1.8599 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.