NSC-12
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 100mg | $1800 | To Be Confirmed |
| 250mg | $3200 | To Be Confirmed |
| 500mg | $4800 | To Be Confirmed |
: Cat #: V2671 CAS #: 102586-30-1 Purity ≥ 98%
Description: NSC-12 (also known as NSC12; NSC 172285) is an orally available pan-FGF trap able to inhibit FGF2/FGFR interaction and endowed with promising antitumor activity.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 484.52 |
|---|---|
| Molecular Formula | C24H34F6O3 |
| CAS No. | 102586-30-1 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 96 mg/mL (198.1 mM)r |
| Water: <1 mg/mLr | |
| Ethanol: 63 mg/mL (130.0 mM) | |
| SMILES Code | C[C@@]12[C@@H]([C@H](O)CC(O)(C(F)(F)F)C(F)(F)F)CC[C@@]1([H])[C@]3([H])CC=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC2 |
| Synonyms | NSC 172285; NSC 172285; NSC-12; NSC-172285; NSC 12; NSC12; NSC172285. |
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.0639 mL | 10.3195 mL | 20.6390 mL | 41.2780 mL |
| 5mM | 0.4128 mL | 2.0639 mL | 4.1278 mL | 8.2556 mL |
| 10mM | 0.2064 mL | 1.0319 mL | 2.0639 mL | 4.1278 mL |
| 20mM | 0.1032 mL | 0.5160 mL | 1.0319 mL | 2.0639 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.