NBI-31772

This product is for research use only, not for human use. We do not sell to patients.

NBI-31772
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$1575Check With Us
200mg$2362Check With Us
500mg$3985Check With Us

Cat #: V7093 CAS #: 374620-70-9 Purity ≥ 99%

Description: NBI-31772 (NBI31772) is a novel and potent non-peptide inhibitor of insulin-like growth factor-1 binding protein (IGFBP) with Kd values are 1 - 24 nM for all six human subtypes.

References: Khawaja XZ. Development of a scintillation proximity assay for human insulin-like growth factor-binding protein 4 compatible with inhibitor high-throughput screening. Anal Biochem. 2007;366(1):80-86.

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Molecular Weight (MW)341.27
Molecular FormulaC17H11NO7
CAS No.374620-70-9
SMILES CodeO=C(C1=CC2=C(C(C(C3=CC=C(O)C(O)=C3)=O)=N1)C=C(O)C(O)=C2)O
SynonymsNBI31772; NBI 31772; NBI-31772;
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.9302 mL14.6512 mL29.3023 mL58.6046 mL
5mM0.5860 mL2.9302 mL5.8605 mL11.7209 mL
10mM0.2930 mL1.4651 mL2.9302 mL5.8605 mL
20mM0.1465 mL0.7326 mL1.4651 mL2.9302 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.