PRT-060318 3HCl
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 250mg | $1340 | To Be Confirmed |
| 500mg | $1950 | To Be Confirmed |
| 1g | $2925 | To Be Confirmed |
: Cat #: V2679 CAS #: N/A Purity ≥ 98%
Description: PRT-060318 3HCl (also known as PRT318 3HCl) is a novel, potent, selective inhibitor of the Syk tyrosine kinase, as an approach to HIT treatment.
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- Physicochemical and Storage Information
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- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 449.81 |
|---|---|
| Molecular Formula | C18H24N6O.3HCl |
| CAS No. | N/A |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 75 mg/mL (166.7 mM)r |
| Water: <1 mg/mLr | |
| Ethanol: 75 mg/mL (166.7 mM) | |
| SMILES Code | O=C(C1=CN=C(N[C@H]2[C@@H](N)CCCC2)N=C1NC3=CC=CC(C)=C3)N |
| Synonyms | PRT318 3HCl; PRT060318 3HCl; PRT 060318 trihydrochloride; PRT-060318; PRT-318; PRT 318; P14-276 3HCl. |
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.2232 mL | 11.1158 mL | 22.2316 mL | 44.4632 mL |
| 5mM | 0.4446 mL | 2.2232 mL | 4.4463 mL | 8.8926 mL |
| 10mM | 0.2223 mL | 1.1116 mL | 2.2232 mL | 4.4463 mL |
| 20mM | 0.1112 mL | 0.5558 mL | 1.1116 mL | 2.2232 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
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Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
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Concentration(final)
C2
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Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.