KIN001-051

This product is for research use only, not for human use. We do not sell to patients.

KIN001-051
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$1875Check With Us
200mg$2812Check With Us
500mg$4745Check With Us

Cat #: V23236 CAS #: 213743-31-8 Purity ≥ 99%

Description: KIN001-051 (Lck inhibitor; C-8863; KIN-001-051) is a novel, potent, cell-permeable and ATP-competitive inhibitor of Lymphocyte-specific protein tyrosine kinase (LCK, IC50s < 1 and 2 nM for C/D isoforms).

References: Arnold LD, et al. Pyrrolo[2,3-d]pyrimidines containing an extended 5-substituent as potent and selective inhibitors of lck I. Bioorg Med Chem Lett. 2000 Oct 2;10(19):2167-70.

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Product Promise

Promise
Molecular Weight (MW)370.45
Molecular FormulaC23H22N4O
CAS No.213743-31-8
SMILES CodeNC1=C2C(N(C3CCCC3)C=C2C4=CC=C(OC5=CC=CC=C5)C=C4)=NC=N1
SynonymsKIN001-051; KIN001051; KIN001 051
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.6994 mL13.4971 mL26.9942 mL53.9884 mL
5mM0.5399 mL2.6994 mL5.3988 mL10.7977 mL
10mM0.2699 mL1.3497 mL2.6994 mL5.3988 mL
20mM0.1350 mL0.6749 mL1.3497 mL2.6994 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.