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cFMS Receptor Inhibitor II

This product is for research use only, not for human use. We do not sell to patients.

cFMS Receptor Inhibitor II
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$1950Check With Us
250mg$3250Check With Us
500mg$4875Check With Us

Cat #: V4438 CAS #: 959860-85-6 Purity ≥ 98%

Description: cFMS Receptor Inhibitor II (BUN60856; BUN-60856) is a novel, cell-permeable and potent CSF1R (Colony stimulating factor 1 receptor) kinase inhibitor with an IC50 of 80 nM.

References: Brenton John SHORT, et al. Compositions and methods for obtaining enriched mesenchymal stem cell cultures. US20160032248A1.

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Product Promise

Promise
Molecular Weight (MW)368.43
Molecular FormulaC₂₃H₂₀N₄O
CAS No.959860-85-6
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
SMILES CodeO=C(C1=C(NC2=CC=C(C)C(C)=C2)C3=CC=C(C4=CC=NC=C4)C=C3N=C1)N
SynonymscFMS Receptor Inhibitor II; cFMS Receptor Inhibitor-II; BUN60856; BUN-60856; BUN 60856
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.7142 mL13.5711 mL27.1422 mL54.2844 mL
5mM0.5428 mL2.7142 mL5.4284 mL10.8569 mL
10mM0.2714 mL1.3571 mL2.7142 mL5.4284 mL
20mM0.1357 mL0.6786 mL1.3571 mL2.7142 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.