PF-06465469
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 100mg | $760 | Check With Us |
| 250mg | $1260 | Check With Us |
| 500mg | $1890 | Check With Us |
: Cat #: V4445 CAS #: 1407966-77-1 Purity ≥ 98%
Description: PF-06465469 (PF06465469) is a novel, potent and covalent inhibitor of ITK (IL-2 inducible T-cell kinase, a nonreceptor tyrosine kinase) with an IC50 of 2 nM.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 523.63 |
|---|---|
| Molecular Formula | C30H33N7O2 |
| CAS No. | 1407966-77-1 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| SMILES Code | O=C(NC1=CC=C(C(C)C)C(C)=C1)C2=CC=CC(C3=NN([C@H]4CN(C(C=C)=O)CCC4)C5=NC=NC(N)=C53)=C2 |
| Synonyms | PF-6465469; PF-06465469; PF 6465469; PF 06465469; PF6465469; PF06465469 |
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 1.9097 mL | 9.5487 mL | 19.0975 mL | 38.1949 mL |
| 5mM | 0.3819 mL | 1.9097 mL | 3.8195 mL | 7.6390 mL |
| 10mM | 0.1910 mL | 0.9549 mL | 1.9097 mL | 3.8195 mL |
| 20mM | 0.0955 mL | 0.4774 mL | 0.9549 mL | 1.9097 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
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Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
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Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
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Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.