ML264

This product is for research use only, not for human use. We do not sell to patients.

ML264
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$1020Check With Us
500mg$1480Check With Us
1g$2220Check With Us

Cat #: V4014 CAS #: 1550008-55-3 Purity ≥ 98%

Description: ML264 is a novel and selective inhibitor of Krüppel-like factor 5 (KLF5) that potently inhibits the proliferation of colorectal cancer cells in vitro through modifications of the cell-cycle profile.

References: Bialkowska A, et al. ML264: An Antitumor Agent that Potently and Selectively Inhibits Krüppel-like Factor Five (KLF5) Expression: A Probe for Studying Colon Cancer Development and Progression.

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Product Promise

Promise
Molecular Weight (MW)384.88
Molecular FormulaC17H21ClN2O4S
CAS No.1550008-55-3
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 10mMr
Water: N/Ar
Ethanol: N/A
SMILES CodeO=C(NCC(N(C(CC1)CCS1(=O)=O)C)=O)/C=C/C2=CC=CC(Cl)=C2
SynonymsCID-51003603; SID 117686865, and SR-03000002171; ML-264; ML264; ML 264
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.5982 mL12.9911 mL25.9821 mL51.9642 mL
5mM0.5196 mL2.5982 mL5.1964 mL10.3928 mL
10mM0.2598 mL1.2991 mL2.5982 mL5.1964 mL
20mM0.1299 mL0.6496 mL1.2991 mL2.5982 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.