Nesiritide

This product is for research use only, not for human use. We do not sell to patients.

Nesiritide
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Size Price Stock
100mg$4390Check With Us
200mg$6585Check With Us
500mg$11115Check With Us

Cat #: V4208 CAS #: 124584-08-3 Purity ≥ 99%

Description: Nesiritide (also known as Brain Natriuretic Peptide-32 human) is a novel and potent agonist of natriuretic peptide receptors (NPRs).

References: Koller KJ, et al. Molecular biology of the natriuretic peptides and their receptors. Circulation. 1992 Oct;86(4):1081-8.

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Molecular Weight (MW)3464.04
Molecular FormulaC143H244N50O42S4
CAS No.124584-08-3
ProtocolIn VitroNesiritide (Brain Natriuretic Peptide-32 human) is an agonist of natriuretic peptide receptor (NPR), with Kd values of 7.3 and 13 pM for NPR-A and NPR-C, respectively.
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM0.2887 mL1.4434 mL2.8868 mL5.7736 mL
5mM0.0577 mL0.2887 mL0.5774 mL1.1547 mL
10mM0.0289 mL0.1443 mL0.2887 mL0.5774 mL
20mM0.0144 mL0.0722 mL0.1443 mL0.2887 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
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Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
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Volume(start)
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=
Concentration(final)
C2
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Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.