LQVTDSGLYRCVIYHPP TFA
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 100mg | $1250 | Check With Us |
| 250mg | $2150 | Check With Us |
| 500mg | $3225 | Check With Us |
: Cat #: V60003 Purity ≥ 99%
Description: LQVTDSGLYRCVIYHPP (LP17) TFA is a novel triggering receptor expressed on myeloid cells (TREM-1) inhibitory peptide.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 2075.27 |
|---|---|
| Molecular Formula | C91H138F3N23O27S |
| Synonyms | LQVTDSGLYRCVIYHPP TFA |
| Protocol | In Vitro | LQVTDSGLYRCVIYHPP (LP17) (10 μM; 24 h) interacts with microglial SYK. LQVTDSGLYRCVIYHPP (LP17) (1 or 10 μM; 24 h) substantially decreases mRNA levels of pro-inflammatory cytokines and chemokines after reoxygenation and remarkably attenuates extracellular protein levels of IL-1β and IL-18 in a microglia oxygen-glucose deprivation (OGD) model. |
|---|---|---|
| In Vivo | LQVTDSGLYRCVIYHPP (LP17) (0.5 or 1 mg/kg; intranasal; daily for 3 days) alleviates ischemia-induced infarction and neuronal injury in mice. |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 0.4819 mL | 2.4093 mL | 4.8187 mL | 9.6373 mL |
| 5mM | 0.0964 mL | 0.4819 mL | 0.9637 mL | 1.9275 mL |
| 10mM | 0.0482 mL | 0.2409 mL | 0.4819 mL | 0.9637 mL |
| 20mM | 0.0241 mL | 0.1205 mL | 0.2409 mL | 0.4819 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start)
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Volume(start)
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This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
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V1
=
Concentration(final)
C2
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Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.