JWG-071
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 100mg | $1500 | To Be Confirmed |
| 200mg | $2250 | To Be Confirmed |
| 500mg | $3795 | To Be Confirmed |
: Cat #: V40505 CAS #: 2250323-50-1 Purity ≥ 99%
Description: JWG-071 is a novel and potent chemical probe.
Top Publications Citing Invivochem Products
Publications Citing InvivoChem Products
Product Promise
- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 612.76 |
|---|---|
| Molecular Formula | C34H44N8O3 |
| CAS No. | 2250323-50-1 |
| SMILES Code | O=C1C2=CC=CC=C2N(C(C)CC)C3=NC(NC4=CC=C(C(N5CCC(N6CCN(C)CC6)CC5)=O)C=C4OC)=NC=C3N1C |
| Synonyms | JWG071; JWG 071; JWG-071 |
| Protocol | In Vitro | JWG-071 inhibits ERK5 and LRRK2 with IC50 of 88 and 109 nM, respectively. |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 1.6320 mL | 8.1598 mL | 16.3196 mL | 32.6392 mL |
| 5mM | 0.3264 mL | 1.6320 mL | 3.2639 mL | 6.5278 mL |
| 10mM | 0.1632 mL | 0.8160 mL | 1.6320 mL | 3.2639 mL |
| 20mM | 0.0816 mL | 0.4080 mL | 0.8160 mL | 1.6320 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.